An efficient catalytic stereoselective route to a key intermediate for the synthesis of the long-lived PGI2 analog ZK 96480 (Cicaprost(TM))

Article abstract of DOI:10.1016/S0040-4039(97)01803-0

An expeditious and stereoselective synthesis of a key chiral intermediate (2) for the synthesis of the therapeutically useful PGI₂ analog Cicaprost(TM) is described.