Enantioselective introduction of a benzenesulfonylmethyl substituent at an unactivated carbon atom via chemoenzymatic methods

Article abstract of DOI:10.1016/S0040-4039(97)01756-5

Introduction of a benzenesulfonylmethyl group at the unactivated γ-carbon of carboxylic acid derivatives has been achieved through a combination of rhodium acetate catalysed carbenoid C-H insertion and baker's yeast mediated kinetic resolution. Access to