
Tetrahedron Asymmetry p. 3415 - 3420 (1997)
Update date:2022-07-29
Topics:
Smith, John R. Lindsay
O'Brien, Peter
Reginato, Gloriana
A simple two step method for the synthesis of three novel C2 symmetric 2,6-diarylalkyloxybenzaldehydes is described. Starting from resorcinol, the route involves double Mitsunobu reaction with chiral alcohols followed by regiospecific lithiation and formylation.
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Doi:10.1021/jacs.1c05732
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(1992)