Toward a transition state analog inhibitor of N-acetylglucosaminyl transferase V

DOI: 10.1016/S0960-894X(97)10087-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2809 - 2812 (1997)

Update date:2022-08-03

Topics:

Authors:

Kaneko, Mitsuaki

Kanie, Osamu

Kajimoto, Tetsuya

Wong, Chi-Huey

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)10087-7

The tumor related enzyme N-acetylglucosaminyltransferase V catalyzes the transfer of GlcNAc to OH-6 of branching Man to give complex oligosaccharide structures. A transition state analog inhibitor of this enzyme was designed and a model compound was synthesized to illustrate the feasibility of the synthetic strategy.

Full text of DOI:10.1016/S0960-894X(97)10087-7

Products guided by the article

Product name:methyl 2,3,4-tri-O-benzyl-7,8-dideoxy-α-D-manno-oct-7-enopyranoside

Cas No:201135-20-8

R&D Labs maybe for 201135-20-8

Dongying J&M Chemical Co., Ltd,

Contact:546-8551108

Address:Room 1219, Zisheng Mansion, Zibo Road, Dongying, Shandong, China
Quzhou Aokai Chemical Co., Ltd.

Contact:86-570-3032832

Address:NO.16 , Laodong Road,Quzhou City, Zhejiang Province,China
NEWSTAR CHEM ENTERPRISE LTD.

Contact:0572-2722882

Address:1201,F3,xinghuibandao,
Nanjing Manhay Medical Technology Co.,Ltd

Contact:86-25-18061468449 13951924040

Address:Building5,Fuzhong Park,Xuanwu District
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.

Contact:13861062998

Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China

Relevant to this article

Stereoselective synthesis of α-C-D-gluco- and D-galactopyranosyl glycosides from an isoprenoid synthon

Doi:10.1016/S0040-4020(98)00926-0
(1998)
Piperazinyl oxazolidinone antibacterial agents containing a pyridine, diazene, or triazene heteroaromatic ring

Doi:10.1021/jm980274l
(1998)
Synthesis and biological activity of a new anti-factor Xa pentasaccharide with a C-interglycosidic bond

Doi:10.1016/S0960-894X(97)00252-7
(1997)
Stereoselective formation of (Z)-γ-substituted allylsilanes by the titanocene(II)-promoted reaction of thioacetals with trialkyl(allyl)silanes

Doi:10.1039/a707177i
(1998)
A New Preparation of Optically Active N-Acyloxazolidinones via Ruthenium-Catalyzed Enantioselective Hydrogenation

Doi:10.1021/jo971733d
(1998)
Nucleosides and Nucleotides. 174. Synthesis of Oligodeoxynucleotides Containing 4′-C-[2-[[N-(2-Aminoethyl)carbamoyl]oxy]ethyl]thymidine and Their Thermal Stability and Nuclease-Resistance Properties

Doi:10.1021/jo9720492
(1998)

Article Doi