Bioorganic and Medicinal Chemistry Letters p. 2809 - 2812 (1997)
Update date:2022-08-03
Topics:
Kaneko, Mitsuaki
Kanie, Osamu
Kajimoto, Tetsuya
Wong, Chi-Huey
The tumor related enzyme N-acetylglucosaminyltransferase V catalyzes the transfer of GlcNAc to OH-6 of branching Man to give complex oligosaccharide structures. A transition state analog inhibitor of this enzyme was designed and a model compound was synthesized to illustrate the feasibility of the synthetic strategy.
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Doi:10.1016/S0040-4020(98)00926-0
(1998)Doi:10.1021/jm980274l
(1998)Doi:10.1016/S0960-894X(97)00252-7
(1997)Doi:10.1039/a707177i
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(1998)
