Synthesis and antiplatelet evaluation of α-methylene-γ-butyrolactone bearing 2-methylquinoline and 8-hydroxyquinoline moieties

DOI: 10.1248/cpb.45.1777

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1777 - 1781 (1997)

Update date:2022-07-30

Topics:

Authors:

Liou, Shorong-Shii

Zhao, Yue-Ling

Chang, Ya-Ling

Teng, Che-Ming

Tzeng, Cherng-Chyi

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Article abstract of DOI:10.1248/cpb.45.1777

In a search for inhibitors of platelet aggregation, some α-methylene- γ-butyrolactones bearing 2-methylquinoline and 8-hydroxyqninoline moieties were synthesized and evaluated for antiplatelet activities against thrombin (Thr)-, arachidonic acid (AA)-, co

Full text of DOI:10.1248/cpb.45.1777

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Product name:8-acetoxy-2-[2-(4-chlorophenyl)-2-oxoethoxy]quinoline

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