Palladium-catalyzed Coupling Reactions of Bromobenzaldehydes with 3,4-Di(tert-butylmethylsilyloxy)-1-alkene to (3,4-Dihydroxyalkenyl)benzaldehydes in the Synthesis of Lipoxin Analogues

DOI: 10.1016/S0040-4039(97)10801-2

Source and publish data:

Tetrahedron Letters p. 1005 - 1008 (1998)

Update date:2022-08-03

Topics:

Authors:

Nokami, Junzo

Furukawa, Akihiko

Okuda, Yoshiaki

Hazato, Atsuo

Kurozumi, Seizi

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Article abstract of DOI:10.1016/S0040-4039(97)10801-2

o-, m-, and p-(3,4-Dihydroxyalkenyl)benzaldehydes were selectively prepared via palladium-catalyzed Heck-type coupling reactions of o-, m-, and p-bromobenzaldehydes with 3,4-di(tert-butyldimethylsilyloxy)-1-alkene.The products were employed for the synthesis of lipoxin analogues, o-, m-, and p-3-hydroxyalkenyl-3,4-dihydroxyalkenylbenzenes.

Full text of DOI:10.1016/S0040-4039(97)10801-2

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