Tetrahedron Letters p. 1005 - 1008 (1998)
Update date:2022-08-03
Topics:
Nokami, Junzo
Furukawa, Akihiko
Okuda, Yoshiaki
Hazato, Atsuo
Kurozumi, Seizi
o-, m-, and p-(3,4-Dihydroxyalkenyl)benzaldehydes were selectively prepared via palladium-catalyzed Heck-type coupling reactions of o-, m-, and p-bromobenzaldehydes with 3,4-di(tert-butyldimethylsilyloxy)-1-alkene.The products were employed for the synthesis of lipoxin analogues, o-, m-, and p-3-hydroxyalkenyl-3,4-dihydroxyalkenylbenzenes.
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