One-pot Mitsunobu-Staudinger preparation of 3-aminocholan-24-oic acid esters from 3-hydroxychlan-24-oic acid esters

Article abstract of DOI:10.1080/00397919808005079

3-Hydroxycholan-24-oic acid esters are easily converted into the corresponding 3-amino derivatives via Mitsunobu reaction with diphenylphosphoryl azide (DPPA) and Staudinger reduction with PPh₃/H₂O of the intermediate azido compound

Full text of DOI:10.1080/00397919808005079

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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One-Pot Mitsunobu-
Staudinger Preparation of 3-
Aminocholan-24-oic Acid Esters
from 3-Hydroxycholan-24-oic
Acid Esters
Pier Lucio Anelli a , Luciano Lattuada a & Fulvio
Uggeri a
a Milano Research Centre, Bracco S.p.A. Via E. Folli,
50, 20134, Milano, Italy
Version of record first published: 20 Aug 2006.
To cite this article: Pier Lucio Anelli, Luciano Lattuada & Fulvio Uggeri (1998): One-
Pot Mitsunobu-Staudinger Preparation of 3-Aminocholan-24-oic Acid Esters from
3-Hydroxycholan-24-oic Acid Esters, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 28:1, 109-117
To link to this article: http://dx.doi.org/10.1080/00397919808005079
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