Tetrahedron p. 3589 - 3606 (1998)
Update date:2022-09-26
Topics:
Vega, Juan A.
Alajarin, Ramon
Vaquero, Juan J.
Alvarez-Builla, Julio
A series of N-alkyl-2-oxoalkanesulfonamides have been synthesized by reacting silyl enol ethers with N-alkyl-sulfamoyl chlorides. Their reactivity towards electrophiles was investigated in order to explore the regio- and stereoselectivity of the process. 2-Oxoalkanesulfonamides were used to prepare 5-(methylsulfamoyl)-1,4-dihydropyridines derivatives.
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