Tetrahedron Letters p. 2421 - 2424 (1998)
Update date:2022-08-05
Topics:
Herbert, John M.
McNeill, Alan H.
Palladium-mediated carbonylation of a 2-iodoindole in the presence of an amine provides an efficient method for the preparation of indole-2- carboxamides. The process is clean and rapid, and appears to be general where the amine component is sufficiently nonvolatile.
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