Synthesis and antiviral activity of novel isodideoxy nucleosides with exocyclic methylene

DOI: 10.1016/S0960-894X(98)00122-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 847 - 852 (1998)

Update date:2022-07-31

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Authors:

Jeong, Lak Shin

Yoo, Su Jeong

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Article abstract of DOI:10.1016/S0960-894X(98)00122-X

Novel isodideoxy nucleosides with exocyclic methylene were synthesized starting from L-xylose utilizing anomeric demethoxylation, Wittig reaction and Mitsunobu reaction as key steps and evaluated for antiviral activity.

Full text of DOI:10.1016/S0960-894X(98)00122-X

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Product name:methyl 2-O-benzyl-3,5-O-isopropylidene-L-xylofuranoside

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