Synthetic Studies on Dynemicin A. New Quinoline Synthesis for C, D and E Rings

Article abstract of DOI:10.1016/S0040-4020(01)85633-7

The important intermediates for the syntheses of dynemicin A model compounds were prepared by coupling between aryltin compounds and α-bromoenone derivatives in the presence of palladium catalyst.The products were transformed under acidic conditions to su