Bioorganic and Medicinal Chemistry Letters p. 1139 - 1144 (1998)
Update date:2022-08-05
Topics:
Tandon, Manish
Wu, Min
Begley, Tadhg P.
Myllyharju, Johanna
Pirskanen, Asta
Kivirikko, Kari
Proline analogs (3-F, 3-Cl, 3-Br, 3,3-cyclopropyl, 3,3-methylene, 3-Me, and 4-Me) were synthesized, incorporated into CbzGlyPheXGlyOEt, and tested as substrate analogues/mechanistic probes for the human prolyl-4-hydroxylase catalyzed hydroxylation reaction. With the exception of the 3-fluoroproline containing peptide, none of these peptides were substrates for the enzyme.
View MoreContact:732.938.2777
Address:5012 Industrial Road Farmingdale, NJ 07727
Hangzhou TJM Chemical Trade Co., Ltd
Contact:86-571-88223276 86-13388481653
Address:2221#,Boyuexuan,1860# Binsheng Road,Binjiang District, Hangzhou CityZhejiang Province, 310051, P. R. China
ClickChem Technology Co., Limited
Contact:+86-0310-6519966/0531-52893837
Address:No.750 Shunhua Road, High-Tech Zone, Jinan city, Shandong China
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.
Contact:15967177856
Address:Genglou Industrial Development Area
hangzhou verychem science and technology co.ltd
website:http://www.verypharm.com
Contact:+86-571-88162785; 88162786
Address:F1502, 753 Shenhua road, Hangzhou, China
Doi:10.1039/a800779i
(1998)Doi:10.1080/00397919708005025
(1997)Doi:10.1016/S0040-4020(00)00316-1
(2000)Doi:10.1021/acs.orglett.6b03087
(2016)Doi:10.1021/om9800849
(1998)Doi:10.1039/c19680001149
(1968)