Bioorganic and Medicinal Chemistry Letters p. 1139 - 1144 (1998)
Update date:2022-08-05
Topics:
Tandon, Manish
Wu, Min
Begley, Tadhg P.
Myllyharju, Johanna
Pirskanen, Asta
Kivirikko, Kari
Proline analogs (3-F, 3-Cl, 3-Br, 3,3-cyclopropyl, 3,3-methylene, 3-Me, and 4-Me) were synthesized, incorporated into CbzGlyPheXGlyOEt, and tested as substrate analogues/mechanistic probes for the human prolyl-4-hydroxylase catalyzed hydroxylation reaction. With the exception of the 3-fluoroproline containing peptide, none of these peptides were substrates for the enzyme.
View MoreDezhou Longteng Chemical Co., Ltd.
website:http://www.sodium-methoxide.cn/
Contact:0086-18866052283
Address:Xinhua Industrial Zone, Dezhou City, Shandong Province, China
Jinzhou Jiutai Pharmaceutical Co.,Ltd
Contact:+86-0416-5179890
Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
zhengzhou Triz Pharma-Tech Co., Ltd
website:http://www.Trizpharma-tech.com
Contact:+86-0371-86597269,53392065
Address:High-tech Industrial Development Zone, Zhengzhou City, NO.7 Holly Street
Contact:+86 021-51698675
Address:1701, Jielong Plaza, No.618 Pingliang Rd, ShangHai,China
Contact:0510-85393305
Address:1619 Huishan Avenue, Huishan District, Wuxi,
Doi:10.1039/a800779i
(1998)Doi:10.1080/00397919708005025
(1997)Doi:10.1016/S0040-4020(00)00316-1
(2000)Doi:10.1021/acs.orglett.6b03087
(2016)Doi:10.1021/om9800849
(1998)Doi:10.1039/c19680001149
(1968)