Bioorganic and Medicinal Chemistry Letters p. 1211 - 1214 (1998)
Update date:2022-07-30
Topics:
Goldring, Alastair O.
Balzarini, Jan
Gilbert, Ian H.
This paper describes the design and synthesis of potential isosteres of triphosphates which should show enhanced metabolic stability and lipophilicity compared to triphosphates. The triphosphate isosteres were then linked to nucleosides and evaluated for their inhibitory activity against HIV infection.
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