Studies on 5-lipoxygenase inhibitors. I. Synthesis and 5-lipoxygenase- inhibitory activity of novel hydroxamic acid derivatives

DOI: 10.1248/cpb.46.966

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 966 - 972 (1998)

Update date:2022-08-05

Topics:

Authors:

Yatabe, Takumi

Kawai, Yoshio

Oku, Teruo

Tanaka, Hirokazu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.966

A series of novel hydroxamates has been prepared and tested for inhibitory activity towards rat polymorphonuclear leukocyte (PMN) 5- lipoxygenase (5-LO) in vitro and towards neutrophil migration in the rat air pouch model of inflammation in vivo. Many 3,4

Full text of DOI:10.1248/cpb.46.966

NII-Electronic Library Service

Products guided by the article

Product name:N-(8-Benzyloxy-2H-thiochromen-3-ylmethyl)-hydroxylamine

Cas No:210972-26-2

R&D Labs maybe for 210972-26-2

NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD

Contact:86-0951-7815345

Address:North side of Qiyuan Road, west side of Yuanfeng Highway, New Material Park, Ningdong Energy and Chemical Industry Base, Ningxia,China
YingYing Pharmaceutical Co.,Ltd

Contact:86-18854126208

Address:55#, yingxiongshan road
ZUNYI CITY BEI YUAN CHEMICAL CO., LTD

website:http://www.china-beiyuan.com

Contact:+86-851-27751258

Address:Shawan Town, Huichuan District, Zunyi City, Guizhou Province, China
SHANGHAI T&W PHARMACEUTICAL CO., LTD.

website:http://www.trustwe.com

Contact:+86-21-61551413

Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China

Relevant to this article

(η⁵-Pentamethylcyclopentadienyl)rhodium(III) complexes bearing η¹-P and η²-phosphino-phenoxide coordinations derived from (2,6-dimethoxyphenyl)d iphenylphosphine: Their preparation and reactions with Lewis bases

Doi:10.1016/S0022-328X(98)00523-3
(1998)
Synthesis of actinomycin analogs: XXIV. Non-symmetric derivatives of actinocin containing benzo-18-crown-6 moiety and tertiary ammonium group

Doi:10.1134/S1070363216120070
(2016)
An efficient synthetic route to a lactone model for the gibberellin A ring

Doi:10.1021/jo00443a042
(1977)
6-Phenyl-6-alkylamido-5,6-dihydro-2H-pyran-2-ones: Novel HIV protease inhibitors

Doi:10.1016/0960-894X(96)00099-6
(1996)
Highly enantioselective synthesis of chiral imides and derived products via chiral base desymmetrisation

Doi:10.1016/S0040-4020(02)00367-8
(2002)
Nitroalkenes as precursors to the aromatic spiroketal skeleton of γ- rubromycin. A Nef-type reaction mediated by Pearlman's catalyst

Doi:10.1016/S0040-4039(98)01046-6
(1998)

Article Doi