A short path synthesis of α-hydroxy ester from aldehyde using (1-ethoxyvinyl)lithium and its application to the syntheses of thymine polyoxin c and uracil polyoxin C

DOI: 10.3987/COM-97-S30

Source and publish data:

Heterocycles p. 87 - 90 (1997)

Update date:2022-08-03

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Authors:

Akita, Hiroyuki

Uchida, Kimio

Chen, Cheng Yu

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Article abstract of DOI:10.3987/COM-97-S30

A short path synthesis of the α-hydroxy esters (4 and 5) from the aldehyde (3) using (1-cthoxyvinyl)lithium and its application to the total syntheses of the pyrimidine nucleoside, thymine polyoxin C (1) and uracil polyoxin C (2), are described.

Full text of DOI:10.3987/COM-97-S30

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