Synthesis of the C28 through C38 segment of okadaic acid using vinylogous urethane aldol chemistry: Part IV

DOI: 10.1016/S0040-4039(98)00974-5

Source and publish data:

Tetrahedron Letters p. 4983 - 4986 (1998)

Update date:2022-08-05

Topics:

Authors:

Dankwardt, John W.

Dankwardt, Sharon M.

Schlessinger, Richard H.

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Article abstract of DOI:10.1016/S0040-4039(98)00974-5

The synthesis of the C-28 through C-38 segment of the marine natural product okadaic acid was accomplished employing a highly enantio- and diasteroselective aldol condensation reaction of a chiral vinylogous urethane enolate. The stereocenter at C-29 was addressed utilizing a diastereoselective hydroboration reaction.

Full text of DOI:10.1016/S0040-4039(98)00974-5

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