
Tetrahedron Letters p. 7661 - 7664 (1998)
Update date:2022-07-29
Topics:
Afonso, Adriano
Kelly
Puar, Mohindar S.
McCombie, Stuart
McPhail, Andrew T.
A method using N-tosyl aziridine for the synthesis of a spiropiperidine 2 (R=H) is described. Cleavage of the N-tosyl group of the intermediate 8 to form the spiropiperidinone 9 was found to proceed in high yield with conc. sulfuric acid. Acylated derivat
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