Synthesis and binding property of an oligonucleotide containing tetrafluorophenoxazine

DOI: 10.1016/S0040-4039(98)01932-7

Source and publish data:

Tetrahedron Letters p. 8385 - 8388 (1998)

Update date:2022-07-30

Topics: Synthesis Experimental Oligonucleotide

Authors:

Wang, Jianying

Lin, Kuei-Ying

Matteucci, Mark D.

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Article abstract of DOI:10.1016/S0040-4039(98)01932-7

A tricyclic pyrimidine nucleoside analog, termed tetrafluorophenoxazine, has been synthesized and incorporated into an oligonucleotide. Tm analyses demonstrate that this analog is capable of enhanced recognition of both a complementary adenine and guanine within a DNA helix.

Full text of DOI:10.1016/S0040-4039(98)01932-7

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