Tetrahedron Letters p. 9361 - 9364 (1998)
Update date:2022-07-31
Topics:
Taylor, Richard E.
Ciavarri, Jeffrey P.
Hearn, Brian R.
The tedanolide and myriaporone classes of natural products represent interesting targets for synthesis because of their structural similarity and biological activity. The asymmetric preparation of a potential common intermediate in the total synthesis of each of these targets is presented. The key step, a Zr-mediated allylation, allows for the efficient preparation of the hydroxypropionate structural unit.
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Doi:10.1016/S0960-894X(99)00405-9
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(2000)Doi:10.1016/S0040-4020(98)00406-2
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(1998)
