A novel method for the synthesis of a C/D-ring synthon of vitamin D derivatives from hyodeoxycholic acid

DOI: 10.1016/S0040-4039(98)80038-5

Source and publish data:

Tetrahedron Letters p. 131 - 132 (1999)

Update date:2022-09-26

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Authors:

Gao, Ling Jie

Zhao, Tian Zeng

Han, Guang Dian

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Article abstract of DOI:10.1016/S0040-4039(98)80038-5

A new C/D ring synthon of vitamin D is readily obtained from hyodeoxycholic acid via permanganate acid oxidation, Jones oxidation, elimination of an acetoxy group and a Norrish type II photochemical reaction, in 47% overall yield.

Full text of DOI:10.1016/S0040-4039(98)80038-5

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