A novel method for the synthesis of a C/D-ring synthon of vitamin D derivatives from hyodeoxycholic acid

DOI: 10.1016/S0040-4039(98)80038-5

Source and publish data:

Tetrahedron Letters p. 131 - 132 (1999)

Update date:2022-09-26

Topics:

Authors:

Gao, Ling Jie

Zhao, Tian Zeng

Han, Guang Dian

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(98)80038-5

A new C/D ring synthon of vitamin D is readily obtained from hyodeoxycholic acid via permanganate acid oxidation, Jones oxidation, elimination of an acetoxy group and a Norrish type II photochemical reaction, in 47% overall yield.

Full text of DOI:10.1016/S0040-4039(98)80038-5

Products guided by the article

Product name:(R)-4-[(1R,3aS,4S,5S,7aR)-5-((1R,4S)-4-Acetoxy-1-methyl-2-oxo-cyclohexyl)-4-carboxymethyl-7a-methyl-octahydro-inden-1-yl]-pentanoic acid methyl ester

Cas No:220463-44-5

R&D Labs maybe for 220463-44-5

Hangzhou utanpharma Co., Ltd

Contact:86-571-87758773

Address:Room604 ,6F, Block A1-3 Xixi Plaza,No. 588 Wenyi West RD, Hangzhou,310012, China
Shanghai Bojing Chemical Co., Ltd.

Contact:021-37122233

Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
Chengdu Sino-Strong Pharmaceutical Co.,Ltd.

website:http://www.sino-strong.com.cn

Contact:+86-28-82666753

Address:459 West haike road,Cross-straits technological industry park, Wenjiang district,Chengdu, P.R.China
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.

website:http://www.zenvasino.com

Contact:+86-138-72658998

Address:Shibeishan Road,Zhijiang, Hubei, China
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37

Relevant to this article

A facile one-pot conversion of acetates of the Baylis-Hillman adducts to [E]-α-methylcinnamic acids

Doi:10.1021/jo981761b
(1999)
Doi:10.1021/ja01027a033
(1968)
4-Hydroxyquinol-2-ones. 86. Synthesis of methyl (ethyl) esters of 1-substituted 4-amino-2-oxoquinoline-3-carboxylic acids

Doi:10.1007/s10593-005-0295-0
(2005)
Reactions of the rhenium allyl hydrido complex Cp*Re(η³-C₃H₅)(CO)(H) with the electrophiles CF₃CO₂H, CF₃SO₃H, NOBF₄, [p-N₂C₆H₄OMe][BF₄] and [Ph₃C][BF₄]

Doi:10.1016/S0022-328X(98)00959-0
(1999)
Germyl- and germylene-bridged complexes of Rh/Ir and subsequent chemistry of a bridging germylene group

Doi:10.1021/ic2021269
(2012)
Reaction of isocyanides with [(PPh₃)₂Pt(η³-CH₂CCPh)] ⁺ and the formation of the indenyl complex trans-[(PPh₃)₂Pt(η ¹-1H-inden-2-yl)(CNC(CH₃)₃)]⁺

Doi:10.1021/om980806w
(1999)

Article Doi