Tetrahedron Letters p. 75 - 78 (1999)
Update date:2022-09-26
Topics:
Chemla, Fabrice
Bernard, Nicolas
Normant, Jean F.
The metalation of 3-trimethylsilyl-1-chloroprop-2-yne and the subsequent reaction with aldehydes affords stereospecifically anti-chlorohydrins which give after treatment with potassium fluoride and NaOH propargylic epoxides with good to excellent yields.
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