Synthetic studies on 2'-substituted-4'-thiocytidine derivatives as antineoplastic agents

Article abstract of DOI:10.1080/15257779908041569

As potential antineoplastic agents, we have synthesized 4'-thioFAC and 4'-thiocytarazid by developing an alternative synthetic method. 4'-ThioFAC showed potent antineoplastic activities in vivo as well as in vitro.

Full text of DOI:10.1080/15257779908041569

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Nucleosides and Nucleotides
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Synthetic Studies on 2′-Substituted-4′-
thiocytidine Derivatives as
Antineoplastic Agents
Yuichi Yoshimura a , Mikari Endo a , Kenji Kitano a , Kohei Yamada a
Shinji Sakata a , Shinji Miura a & Haruhiko Machida a
,
a Biochemicals Division , Yamasa Corporation , 2-10-1 Araoicho,
Choshi, Chiba, 288-0056, Japan
Published online: 04 Oct 2006.
To cite this article: Yuichi Yoshimura , Mikari Endo , Kenji Kitano , Kohei Yamada , Shinji Sakata ,
Shinji Miura & Haruhiko Machida (1999) Synthetic Studies on 2′-Substituted-4′-thiocytidine
Derivatives as Antineoplastic Agents, Nucleosides and Nucleotides, 18:4-5, 815-820, DOI:
10.1080/15257779908041569
To link to this article: http://dx.doi.org/10.1080/15257779908041569
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