Synthetic studies on 2'-substituted-4'-thiocytidine derivatives as antineoplastic agents

DOI: 10.1080/15257779908041569

Source and publish data:

Nucleosides and Nucleotides p. 815 - 820 (1999)

Update date:2022-08-04

Topics:

Authors:

Yoshimura, Yuichi

Endo, Mikari

Kitano, Kenji

Yamada, Kohei

Sakata, Shinji

Miura, Shinji

Machida, Haruhiko

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Article abstract of DOI:10.1080/15257779908041569

As potential antineoplastic agents, we have synthesized 4'-thioFAC and 4'-thiocytarazid by developing an alternative synthetic method. 4'-ThioFAC showed potent antineoplastic activities in vivo as well as in vitro.

Full text of DOI:10.1080/15257779908041569

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