Amino and hydroxy acid based diastereoselective synthesis of 1- deoxygalactostatin and its imino acid derivative

Article abstract of DOI:10.1016/S0040-4039(99)00107-0

1-Deoxygalactostatin (2) and (2S, 3S, 4R, 5S)-trihydroxypipecolic acid (15) have been synthesised from known building blocks derived from glycine, D-valine and L-tartaric acid (eight and seven steps, with 23% and 27% yield, respectively), via a syn-aldol