Tetrahedron Letters p. 2569 - 2572 (1999)
Update date:2022-08-04
Topics:
Sugiyama, Hideyuki
Yokokawa, Fumiaki
Shioiri, Takayuki
Katagiri, Noriko
Oda, Osamu
Ogawa, Hiroshi
The efficient total synthesis of pentosidine (1), an advanced glycation endproduct, was achieved using the asymmetric alkylation of a chiral schiff base (2), the intramolecular guanylation with mercury (II) chloride, and the quaternization accompanied by removal of the trityl group as key steps.
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Doi:10.1021/jm100669j
(2010)Doi:10.1016/j.tetlet.2011.07.084
(2011)Doi:10.1039/a900003h
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(2012)Doi:10.1016/S0040-4020(99)00107-6
(1999)Doi:10.1055/s-1999-2716
(1999)
