Prostanoids and related compounds. VII. Synthesis and inhibitory activity of 1-isoindolinone derivatives possessing inhibitory activity against thromboxane A2 analog (U-46619)-induced vasoconstriction

DOI: 10.1248/cpb.47.529

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 529 - 535 (1999)

Update date:2022-07-30

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Authors:

Kato, Yoshiaki

Takemoto, Masumi

Achiwa, Kazuo

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Article abstract of DOI:10.1248/cpb.47.529

We have synthesized a series of novel 1-isoindolinone derivatives, which inhibited the contraction of pig coronary artery induced by U-46619, a thromboxane A₂ analog.

Full text of DOI:10.1248/cpb.47.529

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