A short chemoenzymatic synthesis of (+)-narciclasine

DOI: 10.1016/S0040-4039(99)00433-5

Source and publish data:

Tetrahedron Letters p. 3077 - 3080 (1999)

Update date:2022-07-29

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Authors:

Gonzalez, David

Martinot, Theodore

Hudlicky, Tomas

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Article abstract of DOI:10.1016/S0040-4039(99)00433-5

The title alkaloid has been synthesized in eight operations from dibromobenzene and ovanillin, via enzymatic oxidation of the former compound, Suzuki coupling and a Bischler-Napieralski type cyclization as the key transformations.

Full text of DOI:10.1016/S0040-4039(99)00433-5

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