Tetrahedron Letters p. 3195 - 3198 (1999)
Update date:2022-08-04
Topics:
Sasaki, Makoto
Maruyama, Takahiro
Sakai, Ryuichi
Tachibana, Kazuo
Synthesis of dysiherbaine model compound 2 and its diastereomer 3 is described. The structurally simplified model compound 2, lacking the hydroxyl and N-methyl groups on the tetrahydropyran ring, induced convulsive behavior in mice upon intracerebral injections.
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