Acta Crystallographica, Section C: Crystal Structure Communications p. 1005 - 1008 (1999)
Update date:2022-08-02
Topics:
Balayiannis, George
Argiris, Ioannis
Papaioannou, Dionissios
Kavounis, Constantin
The title diastereomeric compounds, C18H19ClN4O2, are the products formed when the (2S,3S)- and (2R,3S)-3-(5-amino-6-chloropyrimidinyl)amino-2-(2-benzyloxy)ethyl-oxolanes are treated with triethyl orthoformate in the presence of 4-toluenesulfonic acid. The crystal structure determination unambiguously shows the cis and trans orientations, respectively, of the 2-benzyloxyethyl and the 6-chloropurinyl substituents of the oxolanyl ring.
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