Journal of Fluorine Chemistry p. 82 - 88 (2015)
Update date:2022-07-30
Topics:
Luzina, Elena L.
Popov, Anatoliy V.
A new method is described for producing 3,3,3-trifluoroethyl isocyanate from perfluoroisobutene (PFIB). Isocyanate was used for synthesis of carbamates and ureas. A series of trifluoroethyl-substituted ureas has been tested in the National Cancer Institute (NCI, Bethesda, USA) by the NCI-60 DTP Human Tumor Cell Line Screening Program at a single high dose (10-5 M). The moderate anticancer activity was shown against some types of cancer on the individual human cell lines for leukemia, non-small cell lung cancer and renal cancer.
View MoreA.M FOOD CHEMICAL CO., LIMITED
Contact:86-531-87100375
Address:20Floor,Bblock,1Building,pharma-valley,Jinan,China
Contact:410-273-7300; 800-221-3953
Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd
website:http://www.jlpharms.com
Contact:+86-571-86982636
Address:Rm A606, Fuyi Center, jianqiao street, Jianggan Area
Shanghai birch chemical technology co.,ltd
Contact:+86-21-54096810
Address:No.2588,Jungong Road,Shanghai,China
Contact:86-0510-85133006
Address:hubin road NO157
Doi:10.1021/acs.bioconjchem.1c00176
(2021)Doi:10.1002/ejoc.201600226
(2016)Doi:10.1016/S0040-4020(01)89239-5
(1989)Doi:10.1021/ja01295a041
(1936)Doi:10.1021/ol402869h
(2013)Doi:10.1021/ja01851a068
(1941)