Phytochemistry p. 1055 - 1058 (1991)
Update date:2022-08-03
Topics:
Rosenthal, Gerald A.
L-Cavanine, L-2-amino-4-(guanidinooxy)butyric acid, is a potentially toxic analogue of L-arginine.Canavanine-sensitive organism activate and aminoacylate this non-protein amino acid and thereby create structurally aberrant, canavanine-containing proteins.Incorporation of canavanine into protein can alter the conformation and disrupt the function of the native macromolecule.Production of functionally impaired, canavanyl proteins affects developmental processes and contributes significantly to the expression of canavanine's potent antimetabolic properties in insects.Key Word Index: Canavalia ensiformis; Leguminosae; L-canavanine; non-protein amino acid; toxicity; canavanyl proteins; insects.
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