Synthesis and biological evaluation of (2-hydroxyethyl) 2-deoxy-α-D-threo-pyranoside 3,4,2′-trisphosphate, a mimic of the second messenger inositol 1,4,5-trisphosphate

Article abstract of DOI:10.1080/07328309908544031

(2-Hydroxyethyl) 2-deoxy-α-D-threo-pentopyranoside 3,4,2′-trisphosphate (3) has been prepared starting from allyl-α-D-xylopyranoside. The suitably protected 2-deoxy intermediate obtained by judicious selective protection and deprotection has been phosphor

Full text of DOI:10.1080/07328309908544031

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Journal of Carbohydrate Chemistry
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Synthesis and Biological Evaluation
of (2-Hydroxyethyl) 2-Deoxy-α-
D-Threo-Pyranoside 3,4,2′-
Trisphosphate, A Mimic of the
Second Messenger Inositol 1,4,5-
Trisphosphate
Fabien Roussel , Mauricette Hilly , Françoise Chrétien , Jean-
Pierre Mauger & Yves Chapleur
a Groupe SUCRES, UMR 7565 CNRS - Université Henri
Poincaré-Nancy I , Case 79, BP 239, F-54506 Nancy
Vandoeuvre, (France)
b Unité INSERM U442, Université de Paris Sud , Bât 443,
F-91405 Orsay, (France)
c Groupe SUCRES, UMR 7565 CNRS - Université Henri
Poincaré-Nancy I , Case 79, BP 239, F-54506 Nancy
Vandoeuvre, (France)
d Unité INSERM U442, Université de Paris Sud , Bât 443,
F-91405 Orsay, (France)
e Groupe SUCRES, UMR 7565 CNRS - Université Henri
Poincaré-Nancy I , Case 79, BP 239, F-54506 Nancy
Vandoeuvre, (France)
Published online: 27 Feb 2008.
To cite this article: Fabien Roussel , Mauricette Hilly , Françoise Chrétien , Jean-Pierre
Mauger & Yves Chapleur (1999) Synthesis and Biological Evaluation of (2-Hydroxyethyl)
2-Deoxy-α-D-Threo-Pyranoside 3,4,2′-Trisphosphate, A Mimic of the Second Messenger
Inositol 1,4,5-Trisphosphate, Journal of Carbohydrate Chemistry, 18:6, 697-707, DOI:
10.1080/07328309908544031
To link to this article: http://dx.doi.org/10.1080/07328309908544031
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