Synthesis of methyl 3-amino-4-aryl(or methyl)sulfonyl-2- thiophenecarboxylates from 3-alkoxy-2-aryl(or methyl)-sulfonylacrylonitriles

DOI: 10.1002/jhet.5570360314

Source and publish data:

Journal of Heterocyclic Chemistry p. 659 - 665 (1999)

Update date:2022-08-04

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Authors:

Stephens, Chad E.

Price, Matthew B.

Sowell Sr., J. Walter

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Article abstract of DOI:10.1002/jhet.5570360314

The synthesis of a series of methyl 3-amino-4-aryl(or methyl)sulfonylthiophene-2-carboxylates by reaction of 3-alkoxy-2-aryl(or methyl)sulfonylacrylonitriles with methyl thioglycolate in the presence of triethylamine is described. Hydrolysis/decarboxylati

Full text of DOI:10.1002/jhet.5570360314

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