Nucleosides and Nucleotides p. 1905 - 1910 (1999)
Update date:2022-08-03
Topics:
Hegde, Vishnumurthy R.
Seley, Katherine L.
Chen, Xing
Schneller, Stewart W.
The chiral synthesis of (1S,3S,4S)-1-(3,4-dihydroxycyclopent-1-yl)-1H- thymine (carbocyclic 5,-nor thymidine, 4) has been achieved in 5 steps from (+)-(1R,4S)-4-hydroxy-2-cyclopenten-1-yl acetate (5) and N3-benzoylthymine. Compound 4 is viewed
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