One-Pot Synthesis of α-Chloro Ketones from Secondary Alcohols Using N,N-Dichloro-p-toluenesulfonamide

Article abstract of DOI:10.1246/cl.1990.1125

Various alkyl aryl secondary alcohols reacted with N,N-dichloro-p-toluenesulfonamide (N,N-dichloroamine-T) in CH3CN at 35 deg C to give the corresponding α-chloro ketones in excellent yields under mild and neutral conditions.