A new approach for the determination of the absolute configuration of secondary alcohols by 1H NMR with O-substituted mandelate derivatives

Article abstract of DOI:10.1016/S0040-4039(98)00059-8

It is shown that the cheap and easily prepared mandelic acid esters (or their OAc analogues) are best suited than the expensive, although usually employed. OMe mandelic acid esters to assess both the enantiomeric excesses and absolute configurations of se