Journal of Medicinal Chemistry p. 563 - 567 (1987)
Update date:2022-08-05
Topics:
Vennerstrom, Jonathan L.
Holmes, Thomas J.
The chemical syntheses and biological evaluation of several potential irreversible inhibitors for prostaglandin (PGH) synthase are described.These inhibitors were modeled after the nonsteroidal antiinflammatory (NSAI) drug phenylbutazone(4-n-butyl-1,2-dip
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