Concise and efficient synthesis of 1H-pyrazoles: Reaction of [hydroxy(tosyloxy)iodo]benzene with ethyl 2,3-dioxobutanoate-2-arylhydrazones

Article abstract of DOI:10.1080/00397919108021057

Ethyl 2,3-dioxobutanoate-2-arylhydrazones 1 on treatment with [hydroxy(tosyloxy)iodo]benzene 2 at reflux temperature and followed by heating in the presence of N-ethyldiisopropylamine afforded the cyclized ethyl 1-aryl-4-hydroxy-1H-3-pyrazolecarboxylates 4 in good yield.

Full text of DOI:10.1080/00397919108021057

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Synthetic Communications: An
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Communication of Synthetic
Organic Chemistry
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Concise and Efficient Synthesis
of 1H-Pyrazoles: Reaction of
[Hydroxy(tosyloxy)iodo]benzene
with Ethyl 2,3-
Dioxobutanoate-2-
arylhydrazones
Himatkumar V. Patel a , Kavita A. Vyas a , Sudhanshu
P. Pandey a , Francis Tavares a & P. S. Fernandes a
a N.S.R. Laboratory, Department of Chemistry , St.
Xavier's College , Bombay, 400001, India
Published online: 23 Sep 2006.
To cite this article: Himatkumar V. Patel , Kavita A. Vyas , Sudhanshu P. Pandey ,
Francis Tavares & P. S. Fernandes (1991) Concise and Efficient Synthesis of
1H-Pyrazoles: Reaction of [Hydroxy(tosyloxy)iodo]benzene with Ethyl 2,3-
Dioxobutanoate-2-arylhydrazones, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 21:15-16,
1583-1588, DOI: 10.1080/00397919108021057
To link to this article: http://dx.doi.org/10.1080/00397919108021057
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