A new synthetic entry to 3-carboxamido-4-carboxylic acid derivatives of isoxazole and pyrazole

DOI: 10.1002/jhet.5570370129

Source and publish data:

Journal of Heterocyclic Chemistry p. 175 - 180 (2000)

Update date:2022-07-29

Topics:

Authors:

Vicentini, Chiara B.

Mazzanti, Manuela

Morelli, Carlo F.

Manfrini, Maurizio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570370129

Ethyl 2-amino-3-methoxycarbonyl-4-oxo-2-pentenoate (3) reacts with hydroxylamine or hydrazines to give isoxazole and pyrazole ortho-dicarboxylic acid esters 4 and 5, respectively. Partial hydrolysis of diesters 4 and 5 afforded the corresponding dicarboxy

Full text of DOI:10.1002/jhet.5570370129

Products guided by the article

Product name:ethyl 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(methoxycarbonyl)-5-methyl-3-pyrazolecarboxylate

Cas No:268544-85-0

R&D Labs maybe for 268544-85-0

Liaoning Yufeng Chemical Co.,Ltd.

Contact:86-0419-3418888

Address:The metallurgical industrial zone,shoushan town, Liaoyang, Liaoning, China
Shanghai Zhihua ChemTech Co., Ltd.

Contact:+86-13774313779

Address:Room 817 Suite B 3333 Shenjiang Road
Chengdu Cogon Bio-tech Co., Ltd.

Contact:86-28-85171192

Address:NO.52.YongFeng Rd. Chengdu,610041,P.R.China.
uni source industries limited

Contact:86 21 3772 9386

Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China
JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD

website:http://www.xypharm.com/

Contact:+86-515-84383317

Address:Chenli Road,Costal Chemical Area Binhai,Yancheng, Jiangsu,China

Relevant to this article

4-Substituted Cyclohexanones. Predicting the Facial Selectivity of Nucleophilic Attacks from the Geometrical Changes on Cation-Carbonyl Complexation: An ab Initio Investigation

Doi:10.1021/jo972006l
(1998)
Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 2. Rational design of naphtho[1,2-d]imidazole thrombopoietin mimics

Doi:10.1021/jm0255365
(2002)
Solvent- and concentration-sensitive fluorescence of 2-(3,4,5,6-tetrafluoro-2-hydroxyphenyl)benzoxazole

Doi:10.1002/jhet.5570380118
(2001)
Stereoselective synthesis of novel types of cyclopropyl carbocyclic nucleosides containing quaternary stereogenic centers

Doi:10.1021/jo025599v
(2002)
Gas-phase ionic reactions of benzyl and methoxide anions

Doi:10.1002/(SICI)1099-1395(199707)10:7<531::AID-POC911>3.0.CO;2-C
(1997)
Aerobic synthesis of pyrroles and dihydropyrroles from imines: Palladium(II)-catalyzed intramolecular C-H dehydrogenative cyclization

Doi:10.1002/anie.201300477
(2013)

Article Doi