A new synthetic entry to 3-carboxamido-4-carboxylic acid derivatives of isoxazole and pyrazole

DOI: 10.1002/jhet.5570370129

Source and publish data:

Journal of Heterocyclic Chemistry p. 175 - 180 (2000)

Update date:2022-07-29

Topics:

Authors:

Vicentini, Chiara B.

Mazzanti, Manuela

Morelli, Carlo F.

Manfrini, Maurizio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570370129

Ethyl 2-amino-3-methoxycarbonyl-4-oxo-2-pentenoate (3) reacts with hydroxylamine or hydrazines to give isoxazole and pyrazole ortho-dicarboxylic acid esters 4 and 5, respectively. Partial hydrolysis of diesters 4 and 5 afforded the corresponding dicarboxy

Full text of DOI:10.1002/jhet.5570370129

Products guided by the article

Product name:ethyl 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(methoxycarbonyl)-5-methyl-3-pyrazolecarboxylate

Cas No:268544-85-0

R&D Labs maybe for 268544-85-0

SHANDONG AONA CHEMICAL CO.,LTD.

Contact:86-532-85762926

Address:LIUYUAN TOWN, ZAOZHUANG CITY, SHANGDONG PROVINCE.
Zhejiang Genebest Pharmaceutical Co.,Ltd.

Contact:0086-571-63532866

Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
Hangzhou yi lu biont technology Co., LTD

Contact:+86-571-88152630

Address:Hangzhoushi HuafengRoad Yicheng3Building1001room.
LinHai Cina Chemical Co., LTD.

Contact:0576-85580989

Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Beijing Merson Pharmaceutical Co., Ltd

Contact:0086-10-80484934 0086-10-80484574/

Address:2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road ,Shunyi District , Beijing 101318, P.R.China

Relevant to this article

4-Substituted Cyclohexanones. Predicting the Facial Selectivity of Nucleophilic Attacks from the Geometrical Changes on Cation-Carbonyl Complexation: An ab Initio Investigation

Doi:10.1021/jo972006l
(1998)
Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 2. Rational design of naphtho[1,2-d]imidazole thrombopoietin mimics

Doi:10.1021/jm0255365
(2002)
Solvent- and concentration-sensitive fluorescence of 2-(3,4,5,6-tetrafluoro-2-hydroxyphenyl)benzoxazole

Doi:10.1002/jhet.5570380118
(2001)
Stereoselective synthesis of novel types of cyclopropyl carbocyclic nucleosides containing quaternary stereogenic centers

Doi:10.1021/jo025599v
(2002)
Gas-phase ionic reactions of benzyl and methoxide anions

Doi:10.1002/(SICI)1099-1395(199707)10:7<531::AID-POC911>3.0.CO;2-C
(1997)
Aerobic synthesis of pyrroles and dihydropyrroles from imines: Palladium(II)-catalyzed intramolecular C-H dehydrogenative cyclization

Doi:10.1002/anie.201300477
(2013)

Article Doi