ESTABLISHMENT OF THE STRUCTURE OF GYMNEMAGENIN BY X-RAY ANALYSIS AND THE STRUCTURE OF DEACYLGYMNEMIC ACID

Article abstract of DOI:10.1016/S0040-4039(00)95202-X

The strucuture of gymnemagenin, the sapogenin of antisweet principle of Gymnema syrvestre, was firmly established as 3β,16β,21β,22α,23,28-hexahydroxy-olean-12-ene by the X-ray analysis of the 3β,23;21β,22α-di-O-isopropylidine derivative.On the basis of this result, the structure of deacylgymnemic acid was elucidated as the 3-O-β-glucuronide by comparison of the 13C-NMR spectra.