Journal of Organic Chemistry p. 4893 - 4900 (1999)
Update date:2022-08-03
Topics:
Hanessian, Stephen
Cantin, Louis-David
Andreotti, Daniele
We report the total synthesis of the cytotoxic agent (-)-anthoplalone and the determination of its absolute stereochemistry. The cyclopropane moiety was prepared using a nonracemic bicyclic chloroallyl phosphonamide anion addition to tert-butyl 3,3-dimethyl acrylate. Several pathways were studied to secure the E-trisubstituted olefin of the left part of the molecule.
View MoreWuhan Sunrise Pharmaceutical Technology Co., Ltd
Contact:+86-27-83314682
Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
Wuhan Soleado Technology Co.,Ltd.
Contact:86-2783341481 18971291927
Address:RM2405 Unit 1 Builing 1, Taiyin Tower, Changqing Road,Wuhan China
Wuhan Chemchemical Co., Ltd.(expird)
Contact:15973022782
Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.
Contact:+86-533-3112891
Address:zibo
Taizhou volsen chemical Co., Ltd
website:http://www.volsenchem.com
Contact:+86-576-88869393
Address:Jiaojiang District, Taizhou, Zhejiang, China.
Doi:10.1021/ol005962p
(2000)Doi:10.1021/ol000129d
(2000)Doi:10.1016/S0960-894X(99)00367-4
(1999)Doi:10.1021/ja01277a040
()Doi:10.1021/ol9910058
(1999)Doi:10.1016/S0022-328X(99)00277-6
(1999)
