Bioorganic and Medicinal Chemistry Letters p. 1927 - 1929 (2000)
Update date:2022-09-26
Topics:
Baldwin, Jack E.
Pritchard, Gareth J.
Williamson, Douglas S.
The potent neuroexcitatory activity of kainoid amino acids in the mammalian CNS places new analogues in high demand as tools for neuropharmacological research. A range of 4-arylsulfanyl-substituted kainoids has been synthesised in a parallel fashion via mesylate displacement by a number of aromatic and heteroaromatic thiolates upon (2S,3S,4R)-1-benzoyl-3-tert-butoxycarbonylmethyl-4-methanesulfony loxy pyrrolidine-2-carboxylic acid methyl ester 8, which is obtainable in eight steps from trans-4-hydroxy-L-proline 5. (C) 2000 Elsevier Science Ltd.
View MoreYingkou Sanzheng New Technology Chemical Industry Co., Ltd.
Contact:+86-417-2927806
Address:yingkou
Zouping Mingxing Chemical Co.,Ltd.
website:http://www.zoutong.com.cn
Contact:86-543-2240068 2240067
Address:428 Daixi Third Road Zouping County Shandong Province China
Changzhou Ansciep Chemical Co.,Ltd.
Contact:+86 519 8630 5871
Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
Contact:86-574-26865651
Address:529 YuanBaoShan Road, Beilun District
Goldwills Pharmaceuticals Co., Ltd.
Contact:0916-2237889 13991621155
Address:North Suburb of Hanzhong city, Shaanxi Province
Doi:10.1021/ja01249a024
()Doi:10.1021/jm000945r
(2000)Doi:10.1021/ja507788r
(2014)Doi:10.1021/ja01195a041
(1947)Doi:10.1021/jm000123u
(2000)Doi:10.1007/s11172-005-0133-7
(2004)