Tetrahedron p. 9809 - 9818 (1992)
Update date:2022-08-03
Topics:
Tomas
Camps
Coll
Mele
Pascual
Very precise reaction conditions, using mild fluorination procedures combined with acetonide deprotection, were developed for preparation of 25-fluoroponasterone A from 20-hydroxyecdysone. Biological activity of the new compound was examined and the possible relationship between structure and biological activity in ecdysteroids was studied using MMP2 calculations of the conformations of the side chain of three related compounds: ecdysone, 20-hydroxyecdysone and 25-fluoroponasterone A.
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Doi:10.1039/j39710001884
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(2019)Doi:10.1021/jo00818a003
(1971)Doi:10.1016/S0960-894X(02)00513-9
(2002)Doi:10.1016/S0040-4020(01)93161-8
(1970)
