Open-cyclic warfarin isomerism: 5-hydroxywarfarin

DOI: 10.1007/BF01221901

Source and publish data:

Journal of Crystallographic and Spectroscopic Research p. 583 - 593 (1990)

Update date:2022-08-03

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Authors:

Castleberry, Brian

Valente, Edward J.

Eggleston, Drake S.

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Article abstract of DOI:10.1007/BF01221901

Addition of a 5-hydroxy substituent to warfarin <3-(1-phenyl-3-oxobutyl)-4-hydroxycoumarin> shifts the solution equilibrium in chloroform to favor the open isomeric form over the two cyclic diastereomeric hemiketals.X-ray diffraction analysis reveals 5-hy

Full text of DOI:10.1007/BF01221901

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