Tetrahedron Letters p. 4307 - 4310 (1992)
Update date:2022-09-26
Topics: Characterization Isolation and Purification Removal of chiral auxiliary Synthesis of Chiral Hydrogenolysable Amine Auxiliary Synthesis of ω-Imino Esters Introduction of Chiral Auxiliary Reduction of the ω-Imino Ester Diastereoselective Reduction
Marx
El Bouz
Celerier
Lhommet
Chiral methylbenzylamine is used to prepare ω-amino esters which are then transformed into ω-alkyl lactams with good diastereoselectivity.
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