Trimethylaluminium-facilitated direct amidation of carboxylic acids

DOI: 10.1055/s-0030-1260982

Source and publish data:

Synlett p. 2072 - 2074 (2011)

Update date:2022-07-29

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Authors:

Chung, Seungwon

Uccello, Daniel P.

Choi, Huiwon

Montgomery, Justin I.

Chen, Jinshan

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Article abstract of DOI:10.1055/s-0030-1260982

Free carboxylic acids are converted into amides in moderate to high yields in the presence of a stoichiometric amount of trimethylaluminium and amines at 90°C after 1 hour. Georg Thieme Verlag Stuttgart - New York.

Full text of DOI:10.1055/s-0030-1260982

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