Phosphorus, Sulfur and Silicon and the Related Elements p. 65 - 77 (2007)
Update date:2022-07-29
Topics:
El-Sayed Barakat, Saber
Ghorab, Moustafa M.
Saker, Helmy M.
Abd Rabo, Mahmoud M.
The synthesis of a novel series of quinazolinone derivatives 6-15 having the biologically active thioxo group utilizing 2-isothiocyanato-benzoic acid methyl ester 2 is reported. Their structures have been confirmed on the basis of elemental analyses and (IR, 1H NMR, and mass) spectral data. Preliminary testing for the in vitro antitumor activity of some synthesized compounds against Ehrlich Ascities Carcinoma cells was carried out.
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