PREPARATION OF ENOL LACTONES OF 3,5,7-TRIKETO AND 3,5,7,9-TETRAKETO ACIDS BY THE CONDENSATION OF 4,6-DIMETHOXY-2-PYRONE WITH ANIONS OF MONO- AND DIKETONES

Article abstract of DOI:10.1016/S0040-4039(00)87236-6

Condensations of the anions of acetone, acetophenone, acetylacetone and benzoylacetone with 4,6-dimethoxy-2-pyrone afforded good yields of the corresponding 6 substituted 4-methoxy-2-pyrones which were converted to the 4-hydroxy analogs by demethylation with iodotrimethylsilane.