Bioorganic and Medicinal Chemistry Letters p. 1723 - 1726 (2001)
Update date:2022-08-03
Topics:
Ashton, Wallace T.
Sisco, Rosemary M.
Yang, Yi Tien
Lo, Jane-Ling
Yudkovitz, Joel B.
Cheng, Kang
Goulet, Mark T.
The 2-aryltryptamine class of GnRH receptor antagonists has been modified to incorporate carboxamide and acetamide substituents at the indole 5-position. With either a phenol or methanesulfonamide terminus on the N-aralkyl side chain, potent binding affin
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