Facile Synthesis of Both syn and anti Homoallylic Alcohols from Allyl Chlorides via Organosilicon Intermediates

Article abstract of DOI:10.1246/cl.1994.1773

Highly regio- and diastereoselective synthesis of homoallylic alcohols from allyl chlorides via organosilicon intermediates are attained.While syn homoallylic alcohols were prepared from (Z)-allyl chlorides, anti homoallylic alcohols were obtained from (E)-allyl chlorides. 1-Chloro-2,4-pentadiene reacted at the γ position of the diene system regioselectively.