Synthesis of the L-enantiomer of 4'-C-ethynyl-2'-deoxycytidine.

Article abstract of DOI:10.1271/bbb.65.1879

The L-enantiomer of 4'-C-ethynyl-2'-deoxycytidine (2) was synthesized, but did not show any activity against HIV-1 up to 100 microM.

Full text of DOI:10.1271/bbb.65.1879

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Synthesis of the L-Enantiomer of 4'-C-Ethynyl-2'-
deoxycytidine
Satoru KOHGOa, Hiroaki MITSUYAbc & Hiroshi OHRUIa
a Division of Life Science, Graduate School of Agricultural Science, Tohoku University
b Department of Immunopathophysiology and Internal Medicine II, Kumamoto University
School of Medicine
c Experimental Retrovirology Section, Medicine Branch, Division of Clinical Sciences,
National Cancer Institute
Published online: 22 May 2014.
To cite this article: Satoru KOHGO, Hiroaki MITSUYA & Hiroshi OHRUI (2001) Synthesis of the L-Enantiomer of 4'-C-
Ethynyl-2'-deoxycytidine, Bioscience, Biotechnology, and Biochemistry, 65:8, 1879-1882, DOI: 10.1271/bbb.65.1879
To link to this article: http://dx.doi.org/10.1271/bbb.65.1879
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